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4-Hydroxy Coumarine: a Versatile Reagent for the Synthesis of Heterocyclic and Vanillin Ether Coumarins with Biological Activities
Book chapter

4-Hydroxy Coumarine: a Versatile Reagent for the Synthesis of Heterocyclic and Vanillin Ether Coumarins with Biological Activities

Naceur Hamdi, Mustapha Saoud and Antonio Romerosa
Bioactive Heterocycles V, pp.283-301
Topics in Heterocyclic Chemistry, Springer Berlin Heidelberg
02/06/2007
DOI: https://doi.org/10.1007/7081_2007_062

Abstract

Ethyl Cyanoacetate Heterocyclic Moiety Penicillium Chrysogenum Phenacyl Bromide Triethyl Orthoformate
We report here the synthesis of newly coumarinic derivatives by using 4-hydroxy coumarine as starting material. These newly compounds were screened in vitro for their antimicrobial and antifungal activities. The structures of the synthesized compounds were proved by IR, 1H NMR, 13C NMR and mass-spectral.

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