Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics

V. V Krishhan; Imran H Khan; Paul A Luciw

doi:10.1002/9781119977438.ch11

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Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics

V. V Krishhan, Imran H Khan and Paul A Luciw

Molecular Analysis and Genome Discovery, pp.244-270

John Wiley & Sons, Ltd

04/11/2011

DOI: https://doi.org/10.1002/9781119977438.ch11

Abstract

automation

biomarker detection and molecular profiling

disease‐modifying antirheumatic drugs (DMARDs)

flow cytometer‐based approach

green yttrium aluminum garnet (YAG) laser

Luminex based assays

microbead sandwich immunoassay

microbead suspension array based immunoassays

particle (microbead)‐based flow cytometric assays

This chapter contains sections titled: Introduction Principles of microbead‐based multiplexing Experimental aspects of the multiplex microbead assay Multiplex microbead assay design and comparison with other methods Applications of the multiplex microbead assay system for biomedical research and clinical studies Selected investigational fields for multiplex analysis and examples of applications Challenges and current limitations Summary and future directions Acknowledgements References

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Title: Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics
Creators - without role: V. V Krishhan - California State University, Fresno
Imran H Khan - University of California, Davis
Paul A Luciw - University of California, Davis
Contributors - without role: Ralph Rapley - University of Hertfordshire
Stuart Harbron - The Enzyme Technology Consultancy, UK
Publication Details: Molecular Analysis and Genome Discovery, pp.244-270
Publisher: John Wiley & Sons, Ltd; Chichester, UK
Number of pages: 27
Identifiers: 9952710408331
Academic Unit: King Saud University
Language: English
Resource Type: Book chapter