Abstract
Many traumatic, infectious, vascular, and neoplastic neurological disorders carry poor prognoses for complete neurological recovery. These disorders may result in chronic disability with multiple medical and neurological complications. The common practice of consanguineous marriage in Saudi Arabia results in a high prevalence of many inherited and genetic neurological and metabolic disorders. Many of these children exhibit progressive deterioration in cognitive, language, and/or motor function. Because of the high incidence of such disorders, many of which cannot be characterized, the necessity of facing parents with discussions regarding prognosis is not uncommon.