Abstract
Conference Title: 2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) Conference Start Date: 2017, June 25 Conference End Date: 2017, June 29 Conference Location: Munich, Germany Two-photon fluorescence microscopy provides high resolution information on the anatomy and function of cellular structures located several hundreds of microns deep within biological tissues. However, light scattering poses a fundamental limit to imaging of deeper areas (> 1.5 mm). Implantable microendoscopic probes based on graded index (GRIN) lenses are widely used tools to perform two-photon fluorescence microscopy in otherwise inaccessible regions[1], but the optical performances of with these probes are limited by intrinsic aberrations.