Abstract
Mosquitoes are vectors for many pathogens that cause human diseases including dengue fever, yellow fever and malaria. In an effort to discover new plant based products, essential oils from the flower, leaf and stem of
Echinophora
lamondiana
B.Yildiz et Z.Bahcecioglu were screened for their larvicidal and repellent activity against mosquitoes. Only leaf essential oil showed high larvicidal activity against
Aedes aegypti
L. whereas the other two oils gave very low mortality. Leaf and flower oils showed biting deterrent activity similar to DEET. These oils were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS) to determine the chemical differences among these oils. Three major compounds δ-3-Carene, (
R
)-(-)- α-phellandrene and terpinolene were further screened for their larvicidal and repellent activity using
in vitro
and
in vivo
bioassay systems against
Ae. aegypti
. Pure compound, terpinolene showed biting deterrent activity similar to DEET. δ-3-Carene and terpinolene also showed high activity in
in vivo
bioassays. These materials are being screened against a common malaria mosquito,
Anopheles quadrimaculatus
Say. Data from this study will be presented.