Abstract
To implement personalized medicine effectively at organizational level, it is vital to identify, organize, integrate and leverage multi-dimensional patient data from heterogeneous and distributed resources within an organization. This paper presents the design of a novel informatics framework, to identify, organize and integrate patient's clinical, genomics and environmental data from existing clinical and biomedical resources, and to explore how this patient's data can be leveraged by informatics tools to achieve the goal of personalized medicine.