Miniaturized Drug Delivery System for Biomedical Applications

Khalil Moussi; Mohammed AlDajani; Jurgen Kosel; IEEE

doi:10.1109/NEMS.2019.8915621

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Conference proceeding

Miniaturized Drug Delivery System for Biomedical Applications

Khalil Moussi, Mohammed AlDajani, Jurgen Kosel and IEEE

2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), pp.97-100

01/04/2019

DOI: https://doi.org/10.1109/NEMS.2019.8915621

Abstract

3D printed

Biomembranes

Drug delivery

Drugs

Fabrication

microneedles

micropump

Reservoirs

Three-dimensional displays

Wireless communication

A miniaturized 3D printed drug delivery device powered wirelessly is presented. The device is composed of an electrochemical micropump, a 3D printed reservoir with microneedles, and a wireless powering unit. The electrochemical pump features an expandable (up to 300%) Parylene C micro-bellows membrane fabricated by mold casting, using a two-photon polymerization 3D printing technique. The hollow microneedles are 100 μm in diameter and 300 μm long. The fabrication process offers customizable device properties, where the shape, size, and performance can be tailored to fit a wide range of in vivo drug delivery applications. Delivery of 3.8 ± 0.3 μL within 10 seconds of actuation is demonstrated, using inductive wireless powering at a distance of 10 mm between the primary and secondary coils.

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Details

Title: Miniaturized Drug Delivery System for Biomedical Applications
Creators - without role: Khalil Moussi - King Abdullah University of Science and Technology
Mohammed AlDajani - King Abdullah University of Science and Technology
Jurgen Kosel - King Abdullah University of Science and Technology
IEEE
Publication Details: 2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), pp.97-100
Publisher: IEEE
Identifiers: 9945602908331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Conference proceeding