Abstract
Objects in space have to be represented in order to be stored and analyzed. The three basic abstractions of spatial moving objects are moving point, line or region. The first two abstractions are highly handled. However, moving regions have always been a challenge due to their unstable shape and movement. Researchers are not giving enough attention for managing and querying this particular type of spatial data in order to solve real world problems. Motivated by this fact, we present in this paper an overview on moving regions. We survey region's modeling aspects. Then, we support our research by studying a biomedical case to highlight the importance of using moving regions. The case study illustrates the conceptual aspect of the movement of the colorectal cancer. We also use fuzzy logic thanks for its simplicity and its easy understanding. The combination offers an easier understanding for decision makers.