Abstract
New hexadecan-2-ol (8) and 3-hydroxymethyloctadecanoate (10), together with 14 known compounds (1–7, 9, 11–16) have been isolated from
Grindelia camporum
Greene var.
camporum
. The new compounds were characterized through spectroscopic studies including 1D (1H and 13C NMR) and 2D (COSY, HSQC and HMBC) NMR and mass spectroscopy. The known compounds (Compounds 3 and 4 are hitherto unreported from the family Asteraceae) were identified by comparison of their spectral data with those reported in the literature, chemical evidence or authentic samples [1–3]. The total methanolic extract and the total aqueous extract exhibited cytotoxic and hepatoprotective activities respectively. Also antimicrobial, toxicological (LD
50
, anti-inflammatory, antipyretic and analgesic activities of the different fractions were studied [4–6].
References:
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