Toward large nanostructures

M. Norton; A. Barhoumi; D. Neff; IEEE

doi:10.1109/NANO.2003.1231811

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Conference proceeding

Toward large nanostructures

M. Norton, A. Barhoumi, D. Neff and IEEE

2003 Third IEEE Conference on Nanotechnology, 2003. IEEE-NANO 2003, Vol.1, pp.432-436 vol.2

2003

DOI: https://doi.org/10.1109/NANO.2003.1231811

Abstract

Assembly

Crystals

DNA

Fabrication

Nanostructures

Polymers

Production

Self-assembly

Sequences

Tiles

We describe here the enzymatic production of unusually long sequences of DNA with structural significance for nanostructure self-assembly. A circular template is generated via enzymatic cyclization of a 95 base linear oligonucleotide which then serves as a substrate for DNA polymerases. these 95mer-circles are efficient templates, leading to the production of tandem repeat strands as long as 15,000 bases. Our studies further demonstrate the repetitive nature of the product by enzymatic cleavage giving unit-length oligonucleotides. The rolling circle amplification technique presents a useful method for generating well defined, macroscopic components of DNA nanostructures.

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Details

Title: Toward large nanostructures
Creators - without role: M. Norton - Marshall University
A. Barhoumi - Marshall University
D. Neff - Marshall University
IEEE
Publication Details: 2003 Third IEEE Conference on Nanotechnology, 2003. IEEE-NANO 2003, Vol.1, pp.432-436 vol.2
Publisher: IEEE
Identifiers: 9920032508331
Academic Unit: King Faisal University
Language: English
Resource Type: Conference proceeding