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1,1 '-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
Journal article   Open access  Peer reviewed

1,1 '-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Yahia Nasser Mabkhot, Abdullah Mohammed Al-Majid, Assem Barakat, Saeed Alshahrani and Yamin Siddiqui
Molecules (Basel, Switzerland), Vol.16(8), pp.6502-6511
01/08/2011
DOI: https://doi.org/10.3390/molecules16086502
PMCID: PMC6264270
PMID: 21814162

Abstract

Biochemistry & Molecular Biology Chemistry Chemistry, Multidisciplinary Life Sciences & Biomedicine Physical Sciences Science & Technology
A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by H-1-, C-13-NMR, GCMS, IR, and UV-Vis spectrometry. These compounds represent a new class of sulfur-and nitrogen-containing heterocycles that should also be of interest as new materials.
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https://doi.org/10.3390/molecules16086502View
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