Abstract
Overlapping transcripts (OTs), which have different mRNAs on both strands of the DNAs at the same locus, have been identified from various species. Some OTs are known to decrease their expression level. However, it is still unclear what kinds of OTs affect their expression. Thus, we examined the expression level of human OTs using public microarray data. As a result, we found that positive correlation of gene expression is stronger in human OTs than randomly selected pairs of human mRNAs. In particular, exon-overlapping transcripts showed stronger correlation than non-exon-overlapping transcripts. These results suggest that interaction between different human OTs affect their expression level.