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2-bromo-3,3,3-trifluoropropene: A facile trifluoromethylacetylene anion synthon
Journal article   Peer reviewed

2-bromo-3,3,3-trifluoropropene: A facile trifluoromethylacetylene anion synthon

Alan R. Katritzky, Ming Qi and Adam P. Wells
Journal of fluorine chemistry, Vol.80(2), pp.145-147
01/10/1996

Abstract

2-Bromo-3,3,3-trifluoropropene Organic compounds Trifluoromethylacetylene
The introduction of trifluoromethylacetylene units into organic compounds has been further studied and extended. The direct reaction of two equivalents of Lithium Diisopropylamide with 2-bromo-3,3.3-trifluoropropene gave lithium trifluoromethylacetylide, the anion of which was trapped in greater than 90% overall yield with a variety of electrophiles.

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