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6-Thioguanine as a cause of toxic veno-occlusive disease of the liver
Journal article   Open access  Peer reviewed

6-Thioguanine as a cause of toxic veno-occlusive disease of the liver

M B Satti, K Weinbren and E C Gordon-Smith
Journal of clinical pathology, Vol.35(10), pp.1086-1091
01/10/1982
PMCID: PMC497888
PMID: 6957419

Abstract

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Lesions of hepatic veno-occlusive disease were found in the needle biopsy specimen of one patient suffering from chronic granulocytic leukaemia and in the liver at necropsy of a second patient suffering from acute myeloid leukaemia. The treatment included administration of 6-thioguanine which was the only relevant compound used in the first patient and which was combined with cytosine arabinoside in the second patient.
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https://doi.org/10.1136/jcp.35.10.1086View
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