Abstract
Introduction: Chronic kidney disease (CKD) is a serious, common and costly public health problem and its incidence is on the rise across the globe.
Aim and objectives: The basic aim of the study is to analyse the childhood chronic kidney disease among local population of Pakistan.
Methodology of the study: This cross sectional study was conducted in University of Management and Technology, School of Health Sciences Lahore during March 2018 to October 2018. The data was collected from 100 children age range for this purpose was 1 to 10 years. For this purpose we make two groups of study. One group was control group and the other group was suffering from kidney problems. For this purpose we collect the blood sample for serum analysis. Urea and Creatinine level of blood serum were also calculated by using enzymatic kits.
Results: The data was collected from 100 child patients with mean age range 10.65 +/- 6]5.78 years. According to the K/DOQI scheme, CKD is characterized by stage 1 (mild disease) through stage 5 (ESRD). The inappropriate activation of this system causes hypertension, fluid retention, and inflammatory, thrombotic, and atherogenic effects that may contribute to end-organ damage in the long term. Table 01 shows the values of analysis of statin therapy in patients. It shows the comparison between two groups on the basis of functional values.
Conclusion: It is concluded that children with CKD comprise a very small but important portion of the total CKD population. Whereas disorders associated with its development are well delineated, the availability of valid and widespread information regarding the epidemiology of CKD in children requires additional efforts.