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A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives
Journal article   Peer reviewed

A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

Aansa Hanif, Aniqa Sardar, Meshari Alazmi, Haniya Tariq, Abdul-Hamid Emwas, Xin Gao, Ghayoor Abbas Chotana and Rahman Shah Zaib Saleem
ChemistrySelect (Weinheim), Vol.4(5), pp.1753-1756
07/02/2019
DOI: https://doi.org/10.1002/slct.201803409

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.

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