Abstract
The conditions of the reaction of malononitrile dimer with enaminones and arylidenemalononitrile could be adapted to yield either pyridines or benzene derivatives. A new synthesis of pyrido[1,2-
a
]pyrimidines from the reaction of malononitrile dimer
1
and 2-phenyl-3-piperidin-1-yl-acrylonitrile (
11)
is described. Compound
1
condensed with DMFDMA to yield an enaminonitrile that reacted with hydrazine hydrate to yield
N
',4,6-triamino-2
H
-pyrazolo[3,4-
b
]pyridine-5-carboxamidine (
17
).