Abstract
Carcinoma gall bladder is a relatively uncommon malignancy in Pakistan. Its prognosis is poor with less than 5% of 5 year survival rate. This was an observational, prospective and non interventional study with a sample of 126 patients presenting with benign biliary disease. Out of these 126 cases, 64 were males and 62 patients were females. And 14 out of these were diagnosed of gall bladder malignancy. All the 126 cases were provisionally diagnosed as the cases of cholecystitis with cholelithiasis. The most common presenting complaints were abdominal pain (10 cases) followed by jaundice (4 cases), fever (3 cases) and weight loss (3 cases). Transaminases were raised in 5 cases and hyperbilirubineamia was present in 6 cases. Therefore possibility of presence of gall bladder carcinoma in the evaluation of benign biliary disease must be considered for a better prognosis.