Abstract
Tubulointerstitial nephritis with uveitis (TINU) is an uncommon autoimmune syndrome that involves multiple systems. It usually presents with acute kidney injury (AKI) and unilateral or bilateral uveitis. We present a 15-year-old male, fit and well, who attended emergency room (ER) with a four-month history of epigastric pain associated with nausea, vomiting, and weight loss of 10 kg. Initial clinical and laboratory evaluation confirmed AKI. A diagnostic kidney biopsy confirmed acute tubulointerstitial nephritis, and a slit-lamp examination confirmed acute left anterior uveitis consistent with a diagnosis of TINU. He was initially treated with corticosteroids which resulted in prompt resolution of AKI; however, uveitis persisted necessitating the addition of further immunosuppressants.