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A convenient regioselective synthesis of spirooxindolinopyrrolizidines incorporating the pyrene moiety through a [3+2]-cycloaddition reaction
Journal article   Peer reviewed

A convenient regioselective synthesis of spirooxindolinopyrrolizidines incorporating the pyrene moiety through a [3+2]-cycloaddition reaction

Essam M. Hussein, Saleh A. Ahmed and Ismail I. Althagafi
Heterocyclic communications, Vol.23(5), pp.379-384
26/10/2017
DOI: https://doi.org/10.1515/hc-2017-0036

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A facile one-pot synthesis of spirooxindolinopyr-rolizidines incorporating the pyrene moiety was accomplished in good yields through a 1,3-dipolar cycloaddition reaction of 3-aryl-1-(pyren-1-yl) prop-2-en-1-one derivatives with in situ-generated azomethine ylides.

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