A facile one-pot synthesis of (Z)-α-chloro-α,β-unsaturated esters from alcohols

U. Karama; H. Alshamari; H. Abdelall; M. Sultan

doi:10.1016/j.arabjc.2013.05.011

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A facile one-pot synthesis of (Z)-α-chloro-α,β-unsaturated esters from alcohols

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A facile one-pot synthesis of (Z)-α-chloro-α,β-unsaturated esters from alcohols

U. Karama, H. Alshamari, H. Abdelall and M. Sultan

Arabian journal of chemistry, Vol.10(S2), pp.S1537-S1540

05/2017

DOI: https://doi.org/10.1016/j.arabjc.2013.05.011

Abstract

Halogenations

One pot synthesis

Oxidation

Wittig olefination

Treatment of N-Chlorosuccinimide with (ethoxycarbonylmethylene)-triphenylphosphorane followed by oxidation of alcohol using DMSO/SO3.Pyridine complex as a mild oxidant and trapping of the aldehydes constitutes a stereoselective single flask procedure for the preparation of Z-configured α-chloro-α,β-unsaturated esters.

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Title: A facile one-pot synthesis of (Z)-α-chloro-α,β-unsaturated esters from alcohols
Creators - without role: U. Karama - King Saud University
H. Alshamari - University of Ha'il
H. Abdelall - University of Ha'il
M. Sultan - King Saud University
Publication Details: Arabian journal of chemistry, Vol.10(S2), pp.S1537-S1540
Publisher: Elsevier B.V
Identifiers: 9932058208331
Academic Unit: University Ha'il; King Saud University
Language: English
Resource Type: Journal article