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A facile synthesis of alpha,alpha '-bis(substituted-benzylidene)-cycloalkanones and substituted-benzylidene heteroaromatics: utility of NaOAc as a catalyst for aldol-type reaction
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A facile synthesis of alpha,alpha '-bis(substituted-benzylidene)-cycloalkanones and substituted-benzylidene heteroaromatics: utility of NaOAc as a catalyst for aldol-type reaction

A. F. M. Motiur Rahman, Byeong-Seon Jeong, Dong Hyeon Kim, Jung Ki Park, Eung Seok Lee and Yurngdong Jahng
Tetrahedron, Vol.63(11), pp.2426-2431
12/03/2007

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Utility of NaOAc in glacial HOAc as a catalyst for aldol-type condensation reactions was examined. Reactions of cycloalkanones and selected heteroaromatics with various aldehydes in the presence of NaOAc in glacial HOAc provided alpha,alpha-bis(substituted-benzylidene)cycloalkanones and substituted-benzylidene heteroaromatics, respectively, in good yields. (c) 2007 Elsevier Ltd. All rights reserved.

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