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A highly porous medical metal-organic framework constructed from bioactive curcumin
Journal article   Peer reviewed

A highly porous medical metal-organic framework constructed from bioactive curcumin

Hongmin Su, Fuxing Sun, Jiangtao Jia, Hongming He, Aifei Wang and Guangshan Zhu
Chemical communications (Cambridge, England), Vol.51(26), pp.5774-5777
04/04/2015
DOI: https://doi.org/10.1039/c4cc10159f
PMID: 25722997

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A highly porous bio-MOF, medi-MOF-1, constructed fromZn and the pharmaceutical ingredient curcumin has been successfully synthesized. It can display permanent porosity with a surface area as high as ca. 3002 m(2) g(-1), which exhibits great potential in bioapplications. Its ibuprofen delivery ability, biodegradation and cytotoxicity were also studied.

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