A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes

Reda M. El-Shishtawy; Paulo Almeida; R. M. El-Shishtawy

doi:10.1016/j.tet.2006.05.063

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A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes

Journal article

Peer reviewed

A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes

Reda M. El-Shishtawy, Paulo Almeida and R. M. El-Shishtawy

Tetrahedron, Vol.62(33), pp.7793-7798

14/08/2006

DOI: https://doi.org/10.1016/j.tet.2006.05.063

Abstract

Cyanine dyes

Fluorescent pH sensors

Vilsmeier reaction

Vilsmeier–Haack reaction

A new Vilsmeier-type reaction is suggested for the synthesis of novel indocarbocyanine pH sensors, which are fluorescent when protonated but nonfluorescent upon proton abstraction. These sensors show significant ratiometric UV–visible as well as fluorescence spectral changes upon subtle variation of pHs with p K a values near neutral. [Display omitted]

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Title: A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes
Creators - without role: Reda M. El-Shishtawy - University of Beira Interior
Paulo Almeida - University of Beira Interior
R. M. El-Shishtawy - King Abdulaziz University
Publication Details: Tetrahedron, Vol.62(33), pp.7793-7798
Publisher: Elsevier Ltd
Identifiers: 9935261308331
Academic Unit: King Abdulaziz University
Language: English
Resource Type: Journal article