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A new tyrosinase inhibitor from Crinum yemense as potential treatment for hyperpigmentation
Journal article   Peer reviewed

A new tyrosinase inhibitor from Crinum yemense as potential treatment for hyperpigmentation

O. B. Abdel-Halim, A. M. Marzouk, R. Mothana and N. Awadh
Pharmazie, Vol.63(5), pp.405-407
01/05/2008
PMID: 18557429

Abstract

Chemistry Chemistry, Medicinal Chemistry, Multidisciplinary Life Sciences & Biomedicine Pharmacology & Pharmacy Physical Sciences Science & Technology
A new pyran derivative, 6-hydroxy-2H-pyran-3-carbaldehyde, has been isolated from the methanolic extract of Crinum yemense along with the known alkaloid haemanthamine, benzoic acid and 1,1'-bis(1,1'-carboxyethyl) ether which is isolated from a natural source for the first time. Structure elucidation of these compounds based on spectroscopic evidences. The pyran derivative was found to be a tyrosinase inhibitor more potent than kojic acid.

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