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A novel PCR-RFLP assay for the detection of a polymorphism in the 3 ' of STAT6 gene
Journal article   Peer reviewed

A novel PCR-RFLP assay for the detection of a polymorphism in the 3 ' of STAT6 gene

M Amoli, WER Ollier and A Hajeer
Genes and immunity, Vol.1(5), pp.349-350
01/06/2000
PMID: 11196699

Abstract

Genetics & Heredity Immunology Life Sciences & Biomedicine Science & Technology
We have identified a novel single nucleotide polymorphism at position 2964 (G/A) in the 3' untranslated region of the human STAT6 gene (GeneBank Accession No. U16031). A novel PCR-RFLP method has been devised for this polymorphism using the amplification-created restriction site (ACRS) method Allele frequencies in the UK Caucasian population were found to be 0.33 for allele A and 0.67 for allele G.

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