Sign in
Back
A novel access to highly functionalised β-lactams by regio- and stereoselective 1,3-dipolar cycloaddition reaction
Journal article   Peer reviewed

A novel access to highly functionalised β-lactams by regio- and stereoselective 1,3-dipolar cycloaddition reaction

Natarajan Arumugam, Jayadevan Jayashankaran, Rathna Durga R.S. Manian and Raghavachary Raghunathan
Tetrahedron, Vol.61(35), pp.8512-8516
29/08/2005
DOI: https://doi.org/10.1016/j.tet.2005.06.029

Abstract

Azomethine ylide Cycloaddition β-Lactam
A highly regio- and stereoselective synthesis of novel spiro pyrrolidines/pyrrolizidines containing β-lactam and oxazolone moieties under two different conditions is achieved using [3+2] cycloaddition methodology in moderate to good yield. Graphical Abstract

Metrics

1 Record Views

Details