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A novel method for increased yield of immunocompetent virus for vaccine production
Journal article   Peer reviewed

A novel method for increased yield of immunocompetent virus for vaccine production

A A Qureshi
World journal of microbiology & biotechnology, Vol.7(5), pp.567-570
01/09/1991
PMID: 24425199

Abstract

Cultured human cells exposed to the pesticide emulsifier Atlox, 6 to 8 h prior to Infection with influenza A virus, increased virus production approximately 10-fold. Antibodies against the 'enhanced virus' neutralized plaque formation and reacted equally well with non-enhanced virus in serological tests (haemagglutination-inhibition and radioimmunoassays). The procedure has great potential in cutting costs of production for some virus vaccines.

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