A promising anticancer and antimalarial component from the leaves of Bidens pilosa

Priyanka Kumari; Kanak Misra; Brijesh Singh Sisodia; Uzma Faridi; Suchita Srivastava; Suiab Luqman; Mahendra Pandurang Darokar; Arvind Singh Negi; Madan Mohan Gupta; Subhash Chandra Singh; Jonnala Kotesh Kumar

doi:10.1055/s-0028-1088362

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A promising anticancer and antimalarial component from the leaves of Bidens pilosa

Journal article

Peer reviewed

A promising anticancer and antimalarial component from the leaves of Bidens pilosa

Priyanka Kumari, Kanak Misra, Brijesh Singh Sisodia, Uzma Faridi, Suchita Srivastava, Suiab Luqman, Mahendra Pandurang Darokar, Arvind Singh Negi, Madan Mohan Gupta, Subhash Chandra Singh, …

Planta medica, Vol.75(1), pp.59-61

01/2009

DOI: https://doi.org/10.1055/s-0028-1088362

PMID: 19031368

Abstract

Alkynes - chemistry

Alkynes - isolation & purification

Alkynes - pharmacology

Animals

Antimalarials - chemistry

Antimalarials - isolation & purification

Antimalarials - pharmacology

Antineoplastic Agents, Phytogenic - chemistry

Antineoplastic Agents, Phytogenic - isolation & purification

Antineoplastic Agents, Phytogenic - pharmacology

Bidens - chemistry

Cell Line, Tumor

Drugs, Chinese Herbal - chemistry

Drugs, Chinese Herbal - isolation & purification

Drugs, Chinese Herbal - pharmacology

Erythrocytes - drug effects

Humans

Osmotic Fragility - drug effects

Plant Leaves - chemistry

Plasmodium falciparum - drug effects

Bidens pilosa is used in folk medicine for various applications due to the presence of polyacetylenes, flavonoids, terpenoids, phenylpropanoids and others. Bioactivity-guided fractionation of different extracts of B. pilosa leaf showed potential in vitro anticancer and antimalarial activity and led to the identification of a potential marker compound, phenyl-1,3,5-heptatriyne. Erythrocyte osmotic fragility experiments revealed the various extracts as well as the marker component's toxicity profiles on normal blood cells.

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Title: A promising anticancer and antimalarial component from the leaves of Bidens pilosa
Creators - without role: Priyanka Kumari - Central Institute of Medicinal and Aromatic Plants
Kanak Misra - Central Institute of Medicinal and Aromatic Plants
Brijesh Singh Sisodia - Central Institute of Medicinal and Aromatic Plants
Uzma Faridi - Central Institute of Medicinal and Aromatic Plants
Suchita Srivastava - Central Institute of Medicinal and Aromatic Plants
Suiab Luqman - Central Institute of Medicinal and Aromatic Plants
Mahendra Pandurang Darokar - Central Institute of Medicinal and Aromatic Plants
Arvind Singh Negi - Central Institute of Medicinal and Aromatic Plants
Madan Mohan Gupta - Central Institute of Medicinal and Aromatic Plants
Subhash Chandra Singh
Jonnala Kotesh Kumar - Central Institute of Medicinal and Aromatic Plants
Publication Details: Planta medica, Vol.75(1), pp.59-61
Identifiers: 9933890308331
Academic Unit: University of Tabuk
Language: English
Resource Type: Journal article