Abstract
New non-hydrolyzable analogues of glucosinolates have been prepared. Myrosinase inhibition was observed with modified aglycon moieties, even bulky phenothiazine analogue
6 gave reasonable inhibition. The simplest structure
8 derived from dimethylaminoethanethiol has shown to be the most potent inhibitor with an IC
50 of 3.32
μM.