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A simple and concise catalytic asymmetric entry to tetrahydroxanthenones
Journal article   Peer reviewed

A simple and concise catalytic asymmetric entry to tetrahydroxanthenones

Ramon Rios, Henrik Sunden, Ismail Ibrahem and Armando Cordova
Tetrahedron letters, Vol.48(12), pp.2181-2184
19/03/2007

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The first catalytic asymmetric synthesis of tetrahydroxan then ones is presented. The simple organocatalytic enantioselective domino reactions between salicylic aldehyde derivatives and alpha,beta-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydroxanthenones in moderate to good yields and high enantioselectivities. (c) 2007 Elsevier Ltd. All rights reserved.

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