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A zwitterionic Zn(II) benzothiazole nanohybrid conjugate as hydrolytic DNA cleavage agent
Journal article   Peer reviewed

A zwitterionic Zn(II) benzothiazole nanohybrid conjugate as hydrolytic DNA cleavage agent

Siffeen Zehra, Sartaj Tabassum, Hamad A. Al-Lohedan and Farukh Arjmand
Inorganic chemistry communications, Vol.93, pp.69-72
01/07/2018
DOI: https://doi.org/10.1016/j.inoche.2018.05.008

Abstract

Chemistry Chemistry, Inorganic & Nuclear Physical Sciences Science & Technology
An organic-inorganic hybrid Zn(II) complex has been synthesized in a "zwitterionic" form which crystallizes in triclinic P1 space group possessing labile apical chlorine atoms. DNA interaction studies were performed to enunciate the binding strength. The hydrolytic cleavage potential of the complex was substantiated and the kinetic aspects of the mechanism followed are also discussed.

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