Abstract
OBJECTIVES:Our aim is to investigate the prevalence of hyperuricemia and its relationships to MetS and its components such as hypertension (HTN), glucose intolerance, obesity and hyperlipidemia among Sudanese population.
METHODS:This is a descriptive cross sectional study, held in Khartoum State, Sudan. The study was performed with a sample of 217, adults, attending the clinics set by the Sudanese Society of Hypertension on the occasion of the International day of hypertension from 2016 to 2017. Using World Health Organization WHO) definition, direct measurements were obtained for metabolic syndrome components; anthropometric screenings includedmeasurement of height, weight, and body mass index (BMI). The clinical and biochemical screenings includedmeasurement of blood pressure (BP) and determination of fasting lipid profile, glucose concentrations and serum uric acid.
RESULTS:This study enrolled 217 participants aged 18 – 75 year. MetS prevalence was 25 % in the entire group, (41.8% males, & 58.1% females). Hyperuricemia prevalence was 39.4 % among the group (52.2 % males, 47.7% females). Hyperurecemia prevalence was 40% among MetS cases which was significantly higher than non MetS cases (P < 0.01). In the overall group, SUA concentrations ranged from 3.0 – 12.0 mg/dl, with a mean of 6.0 ± 1.7 mg/dl. Hyperuricemia was significantly positively correlated with BMI (r = .226, p = .001), triglyceride (r = .247, p = .000), and cholesterol (r = .184, p = .007).
CONCLUSION:Hyperuricemia was highly prevalent among Sudanese population. Additionally, for those with hyperuricemia, the odds ratios (95% CI) for metabolic syndrome were 3.61 (95% CI, .591∼ .749) and for fasting blood glucose 0. 478 (95% CI, .392∼.593). SUA can be considered as a better predictor of metabolic syndrome than fasting glucose, th