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AN EFFICIENT MICROWAVE-ASSISTED MULTI-COMPONENT SYNTHESIS OF RHODANINE DERIVATIVES
Journal article   Peer reviewed

AN EFFICIENT MICROWAVE-ASSISTED MULTI-COMPONENT SYNTHESIS OF RHODANINE DERIVATIVES

Santosh A. Jadhav, Mahesh. G. Shioorkar, Omprakash S. Chavan, Aniket P. Sarkate, Mazahar Farooqui, Devanand. B. Shinde and Rajendra K. Pardeshi
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol.25(3-4), pp.201-207
01/01/2016

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Acetonitrile and triethyl amine has been identified as green solvent and base catalyst or the 1 multicomponent synthesis of 5-arylidine-2-(methylthio)-thiazolones (4) in good to excellent yields (83-97%) starting from rhodanine (1), substituted aryl aldehyde (2) and iodomethane (3) by using microwave irradiation method. Present protocol offers advantages of short reaction time, simple workup, and high yields of products.

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