Abstract
Introduction: Antimicrobial resistance (AMR) is known as one of the biggest risks to human beings globally. methicillin-resistant Staphylococcus aureus (MRSA) is one of the most dangerous organisms. It is estimated to kill more people than emphysema, HIV/AIDS, Parkinson's disease and homicide yearly in the US. Worldwide, it is estimated that about three percent of new cases and twenty percent of previously treated cases of tuberculosis are estimated to be caused by types that are resistant to isoniazid and rifampicin. For years, these antituberculosis agents have been excellent medications against tuberculosis, however, recently the effect is inadequate.
Recently, about one-half of multidrug-resistant tuberculosis is successfully managed by the existing medications. Widely drug-resistant tuberculosis has been recognized in more than eighty countries worldwide.
Carbapenem-resistant Enterobacteriaceae spp. and extended-spectrum beta-lactamase-producing Enterobacteriaceae have been recognized in recently. There is a remarkable lack of advancement of new medications active against these multidrug-resistant Gramnegative bacteria, especially those producing carbapenemases, and none of the antibiotics are available are now useful.
In this review, we will discuss the most recent evidence regarding antibiotic over prescribing and their complication.
Aim of work: In this review, we will discuss antibiotic over prescribing and their complication
Methodology: We did a systematic search for Antibiotic over prescribing and their complications using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). We only included full articles. The terms used in the search were: antibiotic, over prescribing, complications.
Conclusions: There is no goal to clarify why antibiotic prescribing in respiratory tract infections (the most frequent primary care) is so great. Physicians must have to benefit and not harm, while respecting the ethical principles of autonomy and justice. But, in the case of ethical conflict, nonmaleficence and justice (at a public and obligatory level) take precedence. We know that we are able to decrease antibiotic prescribing in several of the infections that are needlessly managed without compromising our patients' health. By achieving this, we will do less damage. Furthermore, we know that antibiotics can halt being effective in the short and medium term. The use of the tactics discussed in this paper will help GPs to reduce prescribing of antibiotics.