Abstract
India has rich plant diversity. The people in India are using these plants for medicinal purposes. This practice is common in other developing countries also. The drugs obtained from Different of plants are used in various traditional as well as modern Practices. The present investigation is aimed at investigating the in vitro Successive solvent extract viz., petroleum ether, chloroform, methanol, and water extracts of stem bark of Randia uliginosa. was evaluated for antibacterial activity, against four important bacterial strains S. aureus Escherichia coli, Lacto bacillus, and Enterococcus fecalis by agar-well diffusion method. All the solvent extract showed significant activity against all the tested bacteria, The antibacterial activity is more significant in solvent extracts compared to aqueous extract indicating that the active principle responsible for antibacterial activity is more soluble in organic solvents Comparison of the inhibitory activity of the extracts with the antibiotics Gentamicin revealed that methanol extracts of Randia uliginosa was significantly higher than that of the antibiotics tested. The results suggest that Randia uliginosa. Can be used as a medicament for oral infection