Abstract
In the present study, investigation was done for the effect of camel milk on antioxidants status in streptozotocin diabetic rats. Feeding of 250 ml of raw camel milk was given for normal and diabetic rats for 45 days resulted in significant reduction in plasma glucose and significant increase in plasma insulin levels and body weights. In addition, camel milk caused significant increase in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase, reduced glutathione, vitamin C and vitamin E in liver and kidney of diabetic rats with significant decrease in thiobarbituric acid reactive substances (TBARS) and hydroperoxides formation in liver and kidney, suggesting its role in protection against lipid peroxidation induced membrane damage. The effects of camel milk were compared with glibenclamide. Results of the present study indicated that camel milk showed antioxidant effect in addition to its antidiabetic effect in type 2 diabetic rats.