Abstract
Specifically analyze the relation between skin test reactivity, venom-specific immunoglobulin E (IgE) antibody levels, and acuteness of scientific reaction in patients with insect venom allergy.
According to the study 36 patients (including 15 females) who awarded the allergic reaction history to insect stings were analyzed. The mean age, according the reaction time was 33.4 +/- 15.1 years (range, 4-76 years), similarly, the patients were asessed 43.6 +/- 90 months (range, 1-300 months) after the reactions. The score of scientific reactions were scored according to acuteness, from 1 (cutaneous indicators only) to 3 (anaphylaxis with shock). These scores were compared to scores for skin test reactivity (0 to 5, indicating the log increase in sensitivity from 1 mu g/mL to 0.0001 mu g/mL) and radioallergosorbent test (RAST) "a radioallergosorbent test conducted through blood to perceive particular IgE antibodies and to analyze the substances is allergic or not" levels (0 to 4, indicating venom-specific IgE levels, from undetectable to > 17.5 kilo-units of antigen per liter [kUA/L]).
There was no association observed between skin test reactivity (Spearman's coefficient = 0.15, p = .377) or RAST level (according to Spearman's coefficient = 0.32, p = .061) and the acuteness of reaction. Test of Skin and RAST scores both contrasted promptly from scientific acuteness (p < .05), but there was an important association between skin test reactivity and RAST score (p = .042). There was no association between skin test reactivity and time since reaction (Spearman's coefficient = 0.18, p = .294) nor between RAST and time since reaction (r = 0.1353, p = .438). Patients' elimination tested more than 12 months after their reaction still formed no association between skin test reactivity (p = .681) or RAST score (p = .183) and the acuteness of the scientific reaction.
In venom-allergic patients (in difference to stated outputs in cases of inhalant IgE-mediated allergy), there seems to be no important association between the skin test degree reactivity and venom-specific IgE (determined by RAST) level and the acuteness of the scientific reaction.