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ASSOCIATIONS BETWEEN CIRCULATING LEVELS OF PLASMA OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 AND VASCULAR OUTCOMES IN AFRICAN AMERICAN DIABETIC PATIENTS
Journal article   Peer reviewed

ASSOCIATIONS BETWEEN CIRCULATING LEVELS OF PLASMA OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 AND VASCULAR OUTCOMES IN AFRICAN AMERICAN DIABETIC PATIENTS

Ayobami Eluwole, Ajibola Adedayo, Fasika Tedla, Arye Kremer, Nicole Mastrogiovanni, Mohammed Afzal, Carl Rosenberg, Paul Dreizen, John La Rosa, Mohamed Boutjdir, …
Journal of the American College of Cardiology, Vol.71(11), pp.A1824-A1824
10/03/2018

Abstract

Diabetes Diabetes mellitus Kexin Proprotein convertases Subtilisin
80% had hypertension, 90% had dyslipidemia and 15% had chronic kidney disease. Multiple linear regression analysis showed that PCSK9 was independently associated with VRI in patients with acceptable glycemic control (β= -0.001, p=0.028, r2= 0.136) after adjustment for other independent variables such as age, gender, BMI, dyslipidemia, duration of diabetes, total cholesterol, LDLc, HDLc, creatinine, and triglycerides.

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