Abstract
Objective: To select a subgroup of type-2 diabetics with two additional prespecified risk factors to see that whether there is any benefit of screening such patients.
Methodology: Five hundred twenty six patients were sent for treadmill stress test or thallium scan. Those who had abnormal results were advised coronary angiography. The angiographically proven CAD was correlated with various risk factors to find the relationship between the disease and variables.
Results: Two hundred thirty five (48%) patients had abnormal results and among them 158 (67%) underwent coronary angiography. Among these 21% had evidence of CAD. Coronary artery bypass grafting (CABG) was performed in 35(33%) patients, catheter based intervention (PCI) in 44(40%) patients and 30(27%) patients were not suitable for intervention. Duration of diabetes, smoking, diabetic retinopathy, albuminuria, and peripheral vascular disease were significant predictor of asymptomatic CAD.
Conclusion: This study has demonstrated strong relationship between risk factors and asymptomatic CAD in type2 diabetics.