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Acetylation of the amino group in beta-lactams under aqueous conditions: Effects of ring sizes
Journal article   Peer reviewed

Acetylation of the amino group in beta-lactams under aqueous conditions: Effects of ring sizes

Indrani Banik, Ram Naresh Yadav, Ajay K. Bose and Bimal Krishna Banik
Journal of the Indian Chemical Society, Vol.96(10), pp.1343-1346
01/10/2019

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Monocyclic cis and trans amino beta-lactams are acetylated with 2-bromo-2-phenylacetyl chloride in aqueous sodium bicarbonate solution. The same reaction with 6-aminopenicillanic acid follows a different pathway and produces an oxazolone.

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