Abstract
Six pregnane glycosides were isolated from Caralluma tuberculata, including five ones (1–5). The structures of the isolated compounds were elucidated by the analysis of NMR data and FAB–MS experiments. All the isolated compounds were tested for their antimalarial and antitrypanosomal activities as well as their cytotoxicity against human diploid embryonic cell line (MRC-5).
Five pregnane glycosides were isolated from Caralluma tuberculata (1–5), in addition to a known one (russelioside E, 6). The structures of the isolated compounds were elucidated by the analysis of NMR data and FAB–MS experiments. All the isolated compounds were tested for their antimalarial and antitrypanosomal activities as well as their cytotoxicity against human diploid embryonic cell line (MRC5).