Abstract
Adenoid cystic carcinoma (ACC) is a rare type of breast carcinoma resembling adenoid cystic carcinoma of other sites. this type of tumors usually characterized by the exhibiting dual cell population of luminal and basaloid with specific growth pattern Most of these sub types are triple-negative with basal-like breast features (tumors that are devoid of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression, and express basal cell markers), they are usually low-grade but can be high grade, clinical behavior is indolent despite the nuclear grade, lymph node involvement or distant metastases which is rarely occur. Treatment is either simple mastectomy or lumpectomy. Chemotherapy, radiation and hormonal treatment have limited used in those cases.
•Adenoid cystic carcinoma is mainly seen arises from the salivary glands.•Similar morphology is seen in many other places.•There are 3 major groups of triple negative cancer [basal like phenotype, medullary and medullary like carcinoma and metaplastic carcinoma].•The clinical behavior is indolent despite the grade of the tumor.