Abstract
Aggregation-induced emission (AIE) is an ingenious concept in the field of luminescent molecules. AIE is the energy released in an excited state that in turn is converted into light irrespective of being in either liquid phase or solid phase. Aggregation or crystallization of AIE molecules impedes the free movement of molecules and it resultantly becomes highly fluorescent. It is currently being used for several applications including sensing, diagnostic, protein, DNA or RNA detection, cells and cell organelles imaging. AIEs are highly sensitive and specific for binding with target molecules. In this chapter, we underline different AIE molecules for detection of nucleic acids.