Abstract
This study aimed at alleviating the histopathologic effects of avian influenza virus by a specific nutrient synergy present in Epican Forte (R) (EF). The daily administration of EF at the level of 48.8 mg/mL/bird between 7-14 days of age, to birds challenged at 7-days old with H9N2-avian influenza virus, had different impacts on tracheal deciliation, goblet cell degeneration, mucus accumulation, hypertrophy of mucosal layer, and counts of tracheal heterophils and specific heterophils containing inclusion bodies. Other different impacts by EF were observed in histopathology observations of thoracic air sacs and lungs. The 2 most apparent significant reductions in tracheal histopathologic effects (P < 0.05) due to EF administration were the mucus accumulation and the drop in specific heterophils manifesting a presence of inclusion bodies.