Abstract
Four triterpenoids; one oleanane-, one ursane- and two cycloartane-type triterpenoids, amphipaniculosides A−D (1–4), in addition to one aliphatic alcohol glycoside, amphipaniculoside E (5), together with five known compounds were isolated from the leaves of Amphilophium paniculatum (L.) Kunth. [Display omitted]
•Amphipaniculosides A–D triterpene glycosides, and amphipaniculoside E aliphatic alcohol glycoside, and were isolated from the leaves of Amphilophium paniculatum.
Four new triterpenoids; One oleanane-, one ursane- and two cycloartane-type triterpenoids, named amphipaniculosides A−D, in addition to one new aliphatic alcohol glycoside, named amphipaniculoside E, were isolated from the 1-BuOH fraction of the leaves of Amphilophium paniculatum (L.) Kunth., together with five known compounds, (+)-lyoniresinol 3α-O-β-d-glucopyranoside, (−)-lyoniresinol 3α-O-β-d-glucopyranoside, acteoside (verbascoside), isoacteoside (isoverbascoside), and luteolin 7-O-β-d-glucopyranoside. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments (1H, 13C, DEPT, COSY, ROESY, HSQC, HMBC) in combination with HR-ESI-MS and by comparisons of their physical and spectroscopic data with literature values.