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An Efficient Greener Strategy toward Chemoselective Synthesis of 1,2-Disubstituted Benzimidazoles Catalyzed by Citric Acid
Journal article   Peer reviewed

An Efficient Greener Strategy toward Chemoselective Synthesis of 1,2-Disubstituted Benzimidazoles Catalyzed by Citric Acid

M. Mujahid Alam
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol.32(1), pp.15-21
01/01/2022

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Citric acid (10 mol%) performs as a new green Bronsted acid catalyst for the selective synthesis of 1,2-disubstituted benzimidazoles from a wide range of substituted o-phenylenediamines and aldehydes in moderate to excellent isolated yields (68-97%) using methanol as solvent at ambient temperature.

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