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An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3-ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety
Journal article   Peer reviewed

An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3-ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety

Nesreen S. Ahmed, Tamer S. Saleh and El-Sayed H. El-Mossalamy
Current organic chemistry, Vol.17(2), pp.194-202
01/01/2013
DOI: https://doi.org/10.2174/1385272811317020016

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Novel pyrazoles, bipyrazoles and pyrazol-3-ylpyrazolo[3,4-d]pyrimidines were synthesized using the versatil synthon 2-(1H-benzimidazol-2-yl)-3,3-bis(methylthio) acrylonitrile (1). Reactions were carried out under silent and ultrasonic conditions. In general, improvement in rates and yields were observed when reactions were carried out under ultrasonic irradiation compared with silent condition. Structures of the products were established on analytical and spectral data.

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