Abstract
Data preprocessing has a profound effect on the performance of the learner. Before attempting medical data classification, characteristics of medical datasets, including noise, incompleteness, and the existence of multiple and possibly irrelevant features, need to be addressed. In this paper, we show that selecting the right combination of preprocessing methods has a considerable impact on the classification potential of a dataset. The preprocessing operations considered include the discretization of numeric attributes, the selection of attribute subset(s), and the handling of missing values. The classification is performed by an ant colony optimization algorithm as a case study. Experimental results on 25 real-world medical datasets show that a significant relative improvement in predictive accuracy, exceeding 60% in some cases, is obtained.