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An efficient and green synthesis of polyfunctionalized spirothiazolidin-4-ones using sulfonated mesoporous silica as a reusable catalyst
Journal article   Peer reviewed

An efficient and green synthesis of polyfunctionalized spirothiazolidin-4-ones using sulfonated mesoporous silica as a reusable catalyst

Essam M. Hussein and Saleh A. Ahmed
Chemistry of heterocyclic compounds (New York, N.Y. 1965), Vol.53(10), pp.1148-1155
01/10/2017

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A simple and highly efficient protocol was developed for one-pot synthesis of polyfunctionalized spirothiazolidin-4-ones using sulfonated mesoporous silica (MCM-SO3H) as a heterogenous and reusable acidic catalyst. In comparison to the reported synthetic methods for the synthesis of thiazolidin-4-one and spirothiazolidin-4-one derivatives, this strategy provides superior yields under mild conditions, while avoiding hazardous solvents.

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